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DURECT - 25 Year Stock Price History | DRRX

Historical daily share price chart and data for DURECT since 2000 adjusted for splits and dividends. The latest closing stock price for DURECT as of January 17, 2025 is 0.85.
  • The all-time high DURECT stock closing price was 158.10 on November 06, 2000.
  • The DURECT 52-week high stock price is 1.88, which is 121.2% above the current share price.
  • The DURECT 52-week low stock price is 0.68, which is 20% below the current share price.
  • The average DURECT stock price for the last 52 weeks is 1.18.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
DURECT Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 0.8320 0.7908 0.8700 0.7710 0.8499 13.32%
2024 1.1587 0.5550 1.7800 0.5215 0.7500 27.12%
2023 3.8218 3.6000 8.7200 0.5020 0.5900 -82.95%
2022 5.6450 9.7500 9.7500 3.3900 3.4600 -64.91%
2021 16.0516 21.0000 28.7000 8.9560 9.8590 -52.37%
2020 20.0734 26.1500 28.5000 9.6780 20.7000 -45.53%
2019 11.8597 5.4020 38.0000 5.1200 38.0000 686.59%
2018 14.2259 9.2020 25.1000 4.8310 4.8310 -47.59%
2017 12.6894 13.4000 21.0000 7.7580 9.2180 -31.21%
2016 13.7067 20.4000 20.4000 10.1000 13.4000 -39.37%
2015 20.0206 8.3000 32.3000 8.3000 22.1000 180.03%
2014 14.1437 17.3000 22.2000 6.9570 7.8920 -54.38%
2013 12.3986 9.6000 17.5000 7.7080 17.3000 88.04%
2012 9.5235 12.0000 16.6000 6.9410 9.2000 -22.03%
2011 24.2069 35.9000 37.3000 11.5000 11.8000 -65.80%
2010 25.9768 25.6000 36.1500 19.5000 34.5000 39.68%
2009 24.4722 33.0000 33.9000 14.4000 24.7000 -27.14%
2008 46.5304 62.1000 64.3000 28.7000 33.9000 -47.28%
2007 47.9036 43.9000 69.0000 36.8000 64.3000 44.82%
2006 44.8082 50.7000 63.6000 27.6000 44.4000 -12.43%
2005 46.1865 31.2000 71.8000 26.4000 50.7000 54.57%
2004 26.7017 26.4000 42.3000 12.6000 32.8000 31.20%
2003 24.3238 21.2000 40.0000 11.2000 25.0000 23.76%
2002 62.5330 110.5000 116.0000 19.7000 20.2000 -82.57%
2001 88.3911 111.3000 140.0000 40.0000 115.9000 -3.42%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.026B $0.009B
Durect Corp. is pioneering the treatment of chronic diseases and conditions by developing and commercializing pharmaceutical systems to deliver the right drug to the right place in the right amount at the right time. Its pharmaceutical systems combine engineering innovations and delivery technology from the medical device and drug delivery industries with its proprietary pharmaceutical and biotechnology drug formulations.
Stock Name Country Market Cap PE Ratio
Zoetis (ZTS) United States $74.844B 28.80
Chugai Pharmaceutical (CHGCY) Japan $70.231B 27.36
Takeda Pharmaceutical (TAK) Japan $41.110B 8.56
Sandoz Group AG (SDZNY) Switzerland $19.633B 0.00
Merck (MKKGY) Germany $18.831B 16.86
Astellas Pharma (ALPMY) Japan $17.264B 15.90
United Therapeutics (UTHR) United States $16.024B 15.76
Neurocrine Biosciences (NBIX) United States $14.505B 38.41
Summit Therapeutics (SMMT) United States $14.034B 0.00
Shionogi (SGIOY) Japan $12.114B 12.14
Orion OYJ (ORINY) Finland $7.195B 20.23
Stevanato Group S.p.A (STVN) Italy $6.920B 44.80
Madrigal Pharmaceuticals (MDGL) United States $6.404B 0.00
Corcept Therapeutics (CORT) United States $5.795B 43.90
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $5.456B 0.00
Grifols, S.A (GRFS) Spain $4.999B 0.00
Ionis Pharmaceuticals (IONS) United States $4.963B 0.00
Crinetics Pharmaceuticals (CRNX) United States $3.464B 0.00
Catalyst Pharmaceuticals (CPRX) United States $2.717B 12.31
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.559B 15.30
Recursion Pharmaceuticals (RXRX) United States $2.551B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $2.176B 0.00
Soleno Therapeutics (SLNO) United States $2.021B 0.00
Centessa Pharmaceuticals (CNTA) United Kingdom $1.999B 0.00
Hypermarcas (HYPMY) Brazil $1.932B 0.00
Indivior (INDV) United States $1.606B 6.54
BioCryst Pharmaceuticals (BCRX) United States $1.543B 0.00
Evotec AG (EVO) Germany $1.456B 0.00
Dyne Therapeutics (DYN) United States $1.438B 0.00
Xencor (XNCR) United States $1.346B 0.00
Guardian Pharmacy Services (GRDN) United States $1.310B 0.00
Ocular Therapeutix (OCUL) United States $1.259B 0.00
ARS Pharmaceuticals (SPRY) United States $1.222B 0.00
Harrow (HROW) United States $1.206B 0.00
Ardelyx (ARDX) United States $1.187B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.147B 0.00
Collegium Pharmaceutical (COLL) United States $1.076B 5.87
Enliven Therapeutics (ELVN) United States $1.049B 0.00
Bioventus (BVS) United States $0.815B 25.74
Cronos Group (CRON) Canada $0.761B 0.00
Avadel Pharmaceuticals (AVDL) Ireland $0.747B 0.00
Relay Therapeutics (RLAY) United States $0.747B 0.00
USANA Health Sciences (USNA) United States $0.648B 12.02
Ironwood Pharmaceuticals (IRWD) United States $0.586B 0.00
Elite Pharmaceuticals (ELTP) United States $0.526B 0.00
Verve Therapeutics (VERV) United States $0.520B 0.00
Savara (SVRA) United States $0.503B 0.00
Altimmune (ALT) United States $0.488B 0.00
ProKidney (PROK) United States $0.484B 0.00
Xeris Biopharma Holdings (XERS) United States $0.477B 0.00
Tourmaline Bio (TRML) United States $0.462B 0.00
OmniAb (OABI) United States $0.453B 0.00
Akebia Therapeutics (AKBA) United States $0.452B 0.00
Siga Technologies (SIGA) United States $0.444B 5.19
Esperion Therapeutics (ESPR) United States $0.435B 0.00
Zevra Therapeutics (ZVRA) United States $0.430B 0.00
Oruka Therapeutics (ORKA) United States $0.429B 0.00
Theravance Biopharma (TBPH) Cayman Islands $0.422B 0.00
Organogenesis (ORGO) United States $0.420B 0.00
KalVista Pharmaceuticals (KALV) United States $0.410B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.355B 143.79
Korro Bio (KRRO) United States $0.347B 0.00
Aldeyra Therapeutics (ALDX) United States $0.288B 0.00
Aquestive Therapeutics (AQST) United States $0.283B 0.00
Nature's Sunshine Products (NATR) United States $0.264B 15.68
Heron Therapeutics (HRTX) United States $0.248B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.247B 0.00
Avita Medical (RCEL) United States $0.227B 0.00
Profound Medical (PROF) Canada $0.221B 0.00
Larimar Therapeutics (LRMR) United States $0.213B 0.00
4D Molecular Therapeutics (FDMT) United States $0.212B 0.00
MediWound (MDWD) Israel $0.190B 0.00
Inhibikase Therapeutics (IKT) United States $0.189B 0.00
CytoDyn (CYDY) United States $0.185B 0.00
Aclaris Therapeutics (ACRS) United States $0.184B 0.00
Acrivon Therapeutics (ACRV) United States $0.180B 0.00
VAXART, INC (VXRT) United States $0.168B 0.00
Lyell Immunopharma (LYEL) United States $0.168B 0.00
Lexeo Therapeutics (LXEO) United States $0.168B 0.00
Nektar Therapeutics (NKTR) United States $0.165B 0.00
Silence Therapeutics (SLN) United Kingdom $0.153B 0.00
Jupiter Neurosciences (JUNS) United States $0.146B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.145B 0.00
Nanobiotix S.A (NBTX) France $0.143B 0.00
Telomir Pharmaceuticals (TELO) United States $0.139B 0.00
Champions Oncology (CSBR) United States $0.135B 0.00
Cassava Sciences (SAVA) United States $0.132B 0.00
Enanta Pharmaceuticals (ENTA) United States $0.111B 0.00
Inotiv (NOTV) United States $0.111B 0.00
Achieve Life Sciences (ACHV) Canada $0.106B 0.00
ElectroCore (ECOR) United States $0.104B 0.00
Cardiol Therapeutics (CRDL) Canada $0.099B 0.00
Metagenomi (MGX) United States $0.098B 0.00
Protara Therapeutics (TARA) United States $0.094B 0.00
Pyxis Oncology (PYXS) United States $0.089B 0.00
Fractyl Health (GUTS) United States $0.087B 0.00
Arch Biopartners (ACHFF) Canada $0.085B 0.00
Karyopharm Therapeutics (KPTI) United States $0.083B 0.00
Regulus Therapeutics (RGLS) United States $0.081B 0.00
Assertio Holdings (ASRT) United States $0.079B 20.68
Galectin Therapeutics (GALT) United States $0.078B 0.00
ESSA Pharma (EPIX) Canada $0.078B 0.00
Century Therapeutics (IPSC) United States $0.077B 0.00
Journey Medical (DERM) United States $0.076B 0.00
Context Therapeutics (CNTX) United States $0.076B 0.00
Vivani Medical (VANI) United States $0.071B 0.00
PMV Pharmaceuticals (PMVP) United States $0.071B 0.00
Avalo Therapeutics (AVTX) United States $0.070B 0.00
Mural Oncology (MURA) Ireland $0.068B 0.00
AleAnna (ANNA) United States $0.065B 0.00
Unicycive Therapeutics (UNCY) United States $0.064B 0.00
OptiNose (OPTN) United States $0.064B 0.00
Gain Therapeutics (GANX) United States $0.060B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.059B 0.00
Prelude Therapeutics (PRLD) United States $0.058B 0.00
FibroGen (FGEN) United States $0.058B 0.00
Rafael Holdings (RFL) United States $0.050B 0.00
NRx Pharmaceuticals (NRXP) United States $0.049B 0.00
AlloVir (ALVR) United States $0.047B 0.00
Nutriband (NTRB) United States $0.046B 0.00
Tonix Pharmaceuticals Holding (TNXP) United States $0.044B 0.00
SCYNEXIS (SCYX) United States $0.043B 0.00
Iterum Therapeutics (ITRM) Ireland $0.042B 0.00
CASI Pharmaceuticals (CASI) China $0.041B 0.00
Scienture Holdings (SCNX) United States $0.040B 0.00
Tempest Therapeutics (TPST) United States $0.040B 0.00
VYNE Therapeutics (VYNE) United States $0.040B 0.00
BioVie (BIVI) United States $0.040B 0.00
Surrozen (SRZN) United States $0.039B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.036B 0.00
Incannex Healthcare (IXHL) Australia $0.034B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.031B 0.00
Marinus Pharmaceuticals (MRNS) United States $0.030B 0.00
Citius Pharmaceuticals (CTXR) United States $0.028B 0.00
Vivos Therapeutics (VVOS) United States $0.028B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.026B 0.00
Natural Alternatives (NAII) United States $0.026B 0.00
Enlivex Therapeutics (ENLV) Israel $0.024B 0.00
Lipocine (LPCN) United States $0.023B 0.00
Traws Pharma (TRAW) United States $0.022B 0.00
Mannatech (MTEX) United States $0.021B 0.00
Cosmos Health (COSM) United States $0.020B 0.00
MEI Pharma (MEIP) United States $0.019B 0.00
Carisma Therapeutics (CARM) United States $0.018B 0.00
GlycoMimetics (GLYC) United States $0.017B 0.00
PolyPid (PYPD) Israel $0.016B 0.00
Minerva Neurosciences (NERV) United States $0.016B 0.00
ProPhase Labs (PRPH) United States $0.014B 0.00
Lyra Therapeutics (LYRA) United States $0.012B 0.00
TherapeuticsMD (TXMD) United States $0.012B 0.00
Biomerica (BMRA) United States $0.012B 0.00
Nuvilex (PMCB) United States $0.012B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.012B 0.00
Talphera (TLPH) United States $0.011B 0.00
Relmada Therapeutics (RLMD) United States $0.011B 0.00
Jaguar Animal Health (JAGX) United States $0.010B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.009B 0.00
Ainos (AIMD) United States $0.009B 0.00
Klotho Neurosciences (KLTO) United States $0.009B 0.00
Indaptus Therapeutics (INDP) United States $0.009B 0.00
Addex Therapeutics (ADXN) Switzerland $0.008B 0.00
BioLineRx (BLRX) Israel $0.008B 0.00
Dominari Holdings (DOMH) United States $0.008B 0.00
Conduit Pharmaceuticals (CDT) United States $0.007B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.007B 0.00
Redhill Biopharma (RDHL) Israel $0.007B 0.00
Plus Therapeutics (PSTV) United States $0.007B 0.00
Viracta Therapeutics (VIRX) United States $0.007B 0.00
Xenetic Biosciences (XBIO) United States $0.007B 0.00
Mangoceuticals (MGRX) United States $0.006B 0.00
SciSparc (SPRC) Israel $0.006B 0.00
Aptorum Group (APM) United Kingdom $0.006B 0.00
Phio Pharmaceuticals (PHIO) United States $0.004B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.004B 0.00
Avenue Therapeutics (ATXI) United States $0.004B 0.10
InMed Pharmaceuticals (INM) Canada $0.004B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.004B 0.00
Bio-Path Holdings (BPTH) United States $0.004B 0.00
CERo Therapeutics Holdings (CERO) United States $0.004B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.003B 0.00
TNF Pharmaceuticals (TNFA) United States $0.003B 0.00
Petros Pharmaceuticals (PTPI) United States $0.003B 0.00
Qualigen Therapeutics (QLGN) United States $0.003B 0.00
SHINECO (SISI) China $0.003B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.003B 0.00
Alaunos Therapeutics (TCRT) United States $0.003B 0.00
Heatwurx (PCSA) United States $0.003B 0.00
Clearmind Medicine (CMND) Canada $0.003B 0.00
TransCode Therapeutics (RNAZ) United States $0.002B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.002B 0.00
Aditxt (ADTX) United States $0.002B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.002B 0.00
China SXT Pharmaceuticals (SXTC) China $0.002B 0.00
Universe Pharmaceuticals INC (UPC) China $0.001B 0.00
PainReform (PRFX) Israel $0.000B 0.00
4D Pharma (LBPS) United Kingdom $0.000B 0.00
Procaps Group, S.A (PROC) Luxembourg $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00